President Trump announces 90-day pause on proportional tariffs, companies are developing the infrastructure for multi-agent AI systems, and airborne microplastics enter our food supply through plants
I love reading these at the start of the week. They keep me informed before club meetings and as the week unfolds. Thank you, Chamath, for posting this!
Marty Makary started at FDA last week. Will this story still get suppressed? Brianne was in the NIH trials and just published a book. For science corner lol.
My name is Travis Jackson, I am a practicing physician in Florida. I am writing this message in hopes that it reaches Mr. Chamath Palihapitiya.
I watched your interview with Tucker Carlson a couple of months back and listened to how involved you are with AI in the surgical/medical setting in terms of better outcomes for breast cancer surgeries and reducing medical errors. It was intriguing and brilliant.
Please allow me to give some background on my context here.
I have been in the medical field for over 20 years now. I started my career in surgery as a premed student. During those 10 years I witnessed a lot of IV drug waste and abuse by healthcare professionals. I have spent the last 15 years developing a module that eliminates open access of IV narcotics to prevent drug abuse in hospitals and reducing the cost of these drugs to the patient by only charging to the patient what was actually administered.
Currently, each vial or unit of drug is charged to the patient regardless of how much was administered or wasted. At the end of the surgical procedure or even on the floor what wasn’t dispensed to the patient is “wasted”, which requires a witness, and the entire unit is charged. I witnessed firsthand healthcare professionals who had a drug problem fraudulently signing off on the amount that was wasted into the sharps bin and taking this waste home for recreational use. Some of whom I found out were caught and had to answer to the board of medicine. This is tragic to allow such a fleeting temptation to have such an impact on all of one’s hard work and dedication to earn their medical degree and right to practice. It also drives up the cost of said drugs with so much waste. Regardless if 1cc or the entire unit was administered, the entire unit is charged to the patient.
This is why I have patented a fully secure and automated IV drug dispensing module, MediLock, that houses and dispenses all IV narcotics directly into the IV line. It eliminates open access and only charges to the patient that which was actually administered into the IV line. It also removes the need for syringes and needles which significantly reduces contaminated needle exposure to the healthcare professional.
There is so much more I would like to discuss as far as how it works but it is difficult through text.
I do have a design PDF and a pitch deck I believe would interest you. I am looking to bring this to the market to completely change how IV drugs are administered and charged.
Mr. Palihapitiya, if this interests you please reach out to me and I will send you the design and pitch deck, my contact info is below.
💬 “This isn’t just economic policy — it’s a strategic reset. For decades, we outsourced not just manufacturing, but resilience. Universal tariffs, like them or not, are finally forcing a repricing of risk, leverage, and national interest. Summers argues for tweaks within the current system, but that system was optimized for a world that no longer exists. Trump’s approach may be messy, but it’s movement — and movement forces markets and allies to recalculate. Sometimes flipping the board is the only way to start a new game.”
I'm not an economic nerd or even economic psuedo nerd so I dont pretend to know everything about these tarriff actions but i can say that these seem like an incredibly dumb way to do anything. If the US wants to lead the world into the future and also promote peace globally, then it needs to be an open safe-haven for business and trade with consistent and enforced rules. We can compete with all these countries and we can incentivize capital in our own country by removing regulation or updating tax law. If we just moved on less regulation and consistent and enforced rules there is no country on Earth that could compete with the US. I dont think this necessarily puts me in Larry's camp because I also think doing things through political channels is slow, but there are better ways to do this that would have the US leap ahead incredibly quickly. Regarding China specifically, I'm not sure how the obvious next step for China isnt to expand it's retaliation by limiting or removing access to things they dominate (like rare earths or advanced manufacturing). What's to stop China from just saying, we'll just stop shipping rare earths until tarriff rates come down? Or what's to stop the EU/Australia from working deals with China to increase trade between those countries and leave the US out? Same goes for the EU. What if the EU stops buying as much defense stuff from us? What if they just stop or severly limit importing from the US without tarriffs? The whole tarriff play just seems dumber than dumb and incredibly shortsighted. Trying to play bully is a dumb way to lead.
* Re: A2A/MCP - There should be a standards body (like the W3C) that adopts google's A2A and Anthropic's MCP and carries it forward. That being said, the bottleneck in all of this will be the innacuracy of models. I've said before that I think there's going to be hyper-tuned models (in the mold of phi-4) that are discriminating about the data they are trained on and are small. Then you hyper-tune a router model that is incredibly good about reasoning to categorization of tasks. If you can do that, then you can get to a point where this stuff really works well together. All that being said, I think the great limiting factor is that these models are trained on the information known. Quantum compute will probaby help us get to information unknown and I'd love to be part of or work with people that are working ML/quantum to find relationships between different datasets. I think that's how human imagination works, your brain just traversing many subsets of knowledge graphs and attempting node connections between those subsets until a positive relationship is discovered. those graphs could consist of millions of nodes and there could be millions of subsets. do we get to AGI when those relationships can be established and evaluated in memory? It's just so cool to be alive to witness all this.
* Re: ADHD - When I was growing up, I would have two bowls of cereal and then go sit in chairs for roughtly 7 hours everyday. Toss in the fact that the cereal I was eating had roughly 50g of sugar and it becomes painly obvious why I couldnt pay attention to anything for the part of the day and then crashed soon after public school lunch (which in itself was incredibly unhealthy). I wouldve been diagnosed with ADHD in a heartbeat. However, I also actually have ADHD (diagnosed as an adult in my early 40s). I dont take anything for it yet because my symptoms arent awful and I've learned to cope with some of it by meditating and a few other things. That being said, I've seen kids that eat great/exercise and still cant focus on a single task, are easily distracted, act out because of a baseline feeling of frustration/anxiety from not being able to make a short term decision. These kids could benefit from meditation but they could also benefit from low doses of ADHD medication. I'm not on board with jumping to medication in pretty much any case but I also dont like the idea of demonizing medication when it could be an incredibly life unlock for a few people. I think our society has a tendancy to swing too hard in a single direction, then swing too hard in the other. Katherine makes some good points but she also dismisses a few too easily. For example, my son had a tounge tie that we decided to do nothing about when he was first born. He would have an impossible time feeding, awful acid reflux, and could not sit in a car seat without wailing his head off. We were lucky enough to happen to find a children's pediatrician that told us that if his tounge tie was released then his symptoms would alleviate. Sure enough, right after we got it released, everything was resolved. Literally the day after the surgery he was sitting fine in his car seat and otherstuff. Additionally, if you read the book Breath by James Nestor (absolutely cant recommend it enough), you will see that a series of downstream issues can occur if the tounge tie stays. For example, if you have a tounge tie then your tounge doesnt sit on the roof of your mouth and doesnt push your upper jaw forward, that ends up keeping your nasal passages tight and leads to mouth breathing which can lead to a whole host of issues or if it's a posterior tounge tie, then your bottom jaw doesnt come out and your adult teeth start cramming together and you'll need braces. So while I agree with the overall sentiment of her writeup (at least her twitter thread, I didnt read her article), I'd caution against over generalizing.
I love reading these at the start of the week. They keep me informed before club meetings and as the week unfolds. Thank you, Chamath, for posting this!
Marty Makary started at FDA last week. Will this story still get suppressed? Brianne was in the NIH trials and just published a book. For science corner lol.
https://youtu.be/RV0xlQPv4LA?si=6DmKuSRIxWE-8_Kf
Good afternoon,
My name is Travis Jackson, I am a practicing physician in Florida. I am writing this message in hopes that it reaches Mr. Chamath Palihapitiya.
I watched your interview with Tucker Carlson a couple of months back and listened to how involved you are with AI in the surgical/medical setting in terms of better outcomes for breast cancer surgeries and reducing medical errors. It was intriguing and brilliant.
Please allow me to give some background on my context here.
I have been in the medical field for over 20 years now. I started my career in surgery as a premed student. During those 10 years I witnessed a lot of IV drug waste and abuse by healthcare professionals. I have spent the last 15 years developing a module that eliminates open access of IV narcotics to prevent drug abuse in hospitals and reducing the cost of these drugs to the patient by only charging to the patient what was actually administered.
Currently, each vial or unit of drug is charged to the patient regardless of how much was administered or wasted. At the end of the surgical procedure or even on the floor what wasn’t dispensed to the patient is “wasted”, which requires a witness, and the entire unit is charged. I witnessed firsthand healthcare professionals who had a drug problem fraudulently signing off on the amount that was wasted into the sharps bin and taking this waste home for recreational use. Some of whom I found out were caught and had to answer to the board of medicine. This is tragic to allow such a fleeting temptation to have such an impact on all of one’s hard work and dedication to earn their medical degree and right to practice. It also drives up the cost of said drugs with so much waste. Regardless if 1cc or the entire unit was administered, the entire unit is charged to the patient.
This is why I have patented a fully secure and automated IV drug dispensing module, MediLock, that houses and dispenses all IV narcotics directly into the IV line. It eliminates open access and only charges to the patient that which was actually administered into the IV line. It also removes the need for syringes and needles which significantly reduces contaminated needle exposure to the healthcare professional.
There is so much more I would like to discuss as far as how it works but it is difficult through text.
I do have a design PDF and a pitch deck I believe would interest you. I am looking to bring this to the market to completely change how IV drugs are administered and charged.
Mr. Palihapitiya, if this interests you please reach out to me and I will send you the design and pitch deck, my contact info is below.
Sales@MediLock.org
💬 “This isn’t just economic policy — it’s a strategic reset. For decades, we outsourced not just manufacturing, but resilience. Universal tariffs, like them or not, are finally forcing a repricing of risk, leverage, and national interest. Summers argues for tweaks within the current system, but that system was optimized for a world that no longer exists. Trump’s approach may be messy, but it’s movement — and movement forces markets and allies to recalculate. Sometimes flipping the board is the only way to start a new game.”
Here's my page for more on this topic: https://substack.com/@chaserierson
Couple O' Thoughts:
* Re: Tarrifs -
I'm not an economic nerd or even economic psuedo nerd so I dont pretend to know everything about these tarriff actions but i can say that these seem like an incredibly dumb way to do anything. If the US wants to lead the world into the future and also promote peace globally, then it needs to be an open safe-haven for business and trade with consistent and enforced rules. We can compete with all these countries and we can incentivize capital in our own country by removing regulation or updating tax law. If we just moved on less regulation and consistent and enforced rules there is no country on Earth that could compete with the US. I dont think this necessarily puts me in Larry's camp because I also think doing things through political channels is slow, but there are better ways to do this that would have the US leap ahead incredibly quickly. Regarding China specifically, I'm not sure how the obvious next step for China isnt to expand it's retaliation by limiting or removing access to things they dominate (like rare earths or advanced manufacturing). What's to stop China from just saying, we'll just stop shipping rare earths until tarriff rates come down? Or what's to stop the EU/Australia from working deals with China to increase trade between those countries and leave the US out? Same goes for the EU. What if the EU stops buying as much defense stuff from us? What if they just stop or severly limit importing from the US without tarriffs? The whole tarriff play just seems dumber than dumb and incredibly shortsighted. Trying to play bully is a dumb way to lead.
* Re: A2A/MCP - There should be a standards body (like the W3C) that adopts google's A2A and Anthropic's MCP and carries it forward. That being said, the bottleneck in all of this will be the innacuracy of models. I've said before that I think there's going to be hyper-tuned models (in the mold of phi-4) that are discriminating about the data they are trained on and are small. Then you hyper-tune a router model that is incredibly good about reasoning to categorization of tasks. If you can do that, then you can get to a point where this stuff really works well together. All that being said, I think the great limiting factor is that these models are trained on the information known. Quantum compute will probaby help us get to information unknown and I'd love to be part of or work with people that are working ML/quantum to find relationships between different datasets. I think that's how human imagination works, your brain just traversing many subsets of knowledge graphs and attempting node connections between those subsets until a positive relationship is discovered. those graphs could consist of millions of nodes and there could be millions of subsets. do we get to AGI when those relationships can be established and evaluated in memory? It's just so cool to be alive to witness all this.
* Re: ADHD - When I was growing up, I would have two bowls of cereal and then go sit in chairs for roughtly 7 hours everyday. Toss in the fact that the cereal I was eating had roughly 50g of sugar and it becomes painly obvious why I couldnt pay attention to anything for the part of the day and then crashed soon after public school lunch (which in itself was incredibly unhealthy). I wouldve been diagnosed with ADHD in a heartbeat. However, I also actually have ADHD (diagnosed as an adult in my early 40s). I dont take anything for it yet because my symptoms arent awful and I've learned to cope with some of it by meditating and a few other things. That being said, I've seen kids that eat great/exercise and still cant focus on a single task, are easily distracted, act out because of a baseline feeling of frustration/anxiety from not being able to make a short term decision. These kids could benefit from meditation but they could also benefit from low doses of ADHD medication. I'm not on board with jumping to medication in pretty much any case but I also dont like the idea of demonizing medication when it could be an incredibly life unlock for a few people. I think our society has a tendancy to swing too hard in a single direction, then swing too hard in the other. Katherine makes some good points but she also dismisses a few too easily. For example, my son had a tounge tie that we decided to do nothing about when he was first born. He would have an impossible time feeding, awful acid reflux, and could not sit in a car seat without wailing his head off. We were lucky enough to happen to find a children's pediatrician that told us that if his tounge tie was released then his symptoms would alleviate. Sure enough, right after we got it released, everything was resolved. Literally the day after the surgery he was sitting fine in his car seat and otherstuff. Additionally, if you read the book Breath by James Nestor (absolutely cant recommend it enough), you will see that a series of downstream issues can occur if the tounge tie stays. For example, if you have a tounge tie then your tounge doesnt sit on the roof of your mouth and doesnt push your upper jaw forward, that ends up keeping your nasal passages tight and leads to mouth breathing which can lead to a whole host of issues or if it's a posterior tounge tie, then your bottom jaw doesnt come out and your adult teeth start cramming together and you'll need braces. So while I agree with the overall sentiment of her writeup (at least her twitter thread, I didnt read her article), I'd caution against over generalizing.
Thanks Chamath. Great stuff
Episode 132 of All-In you dunk on golf- are you a fan now??
The All In episode this week was epic! I loved that fiery debate!!
Thanks Chamath! I’m a pediatrician, technologist at PreventScripts and an All In Fan! Appreciate you!